세륨옥사이드나노입자(Cerium oxide nano particles: CNPs)를 함유한 치면열구전색재의 Streptococcus mutans 부착량 변화
Changes in the amount of adhesion of Streptococcus mutans to pit and fissure sealant incorporating cerium oxide nano particles(CNPs)
이성숙, 박영민, 김동애,
소속 상세정보
이성숙 ( Lee Seong-Sook ) - Yeoju Institute of Technology Department of Dental Hygiene
박영민 ( Park Young-Min ) - Yeoju Institute of Technology Department of Dental Hygiene
김동애 ( Kim Dong-Ae ) - Yeoju Institute of Technology Department of Dental Hygiene
Abstract
Objectives: The aim of this study was to investigated the surface roughness and change in the amount of adhesion of Streptococcus mutans to the commercial pit and fissure sealant containing cerium oxide nano particles(CNPs).
Methods: The CNPs was incorporated into a commercial pit and fissure sealant at 0-4.0 wt%. Disk Specimens (φ 10 mm × 2 mm) were prepared by light polymerization the front and back for 40s. Average surface roughness was measured and Streptococcus mutans adhesion was observed under confocal laser scanning microscopy (CLSM) after 24 hour. Data were statistically analyzed by one-way ANOVA and Tukey HSDa post-hoc test.
Results: Difference of the surface roughness(Ra) between groups was not statistically significant in both non CNPs group and CNPs group(p>0.05). In CNPs group, the amount of S. mutans adhesion was significantly different between control group and decreased in order of CNPs 4.0, CNPs 0.5, CNPs 1.0 and CNPs 2.0(p<0.05).
Conclusions: Within the limitation of this study, these aspects of oral bacteria performances suggest potential usefulness of the CNPs incorporation, especially CNPs 1% and 2%, in pit and fissure sealant for inducing antibacterial effect.
키워드
뮤탄스균; 세균부착; 세륨옥사이드나노입자; 치면열구전색재
Bacterial adhesion; Cerium oxide nano particles; Pit and fissure sealants; Streptococcus mutans
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